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Shop all 595 productsSynology-validated enterprise flash for cache and small all-flash pools.
The Synology SAT5221-480G is a 480GB 2.5-inch SATA enterprise SSD built for Synology NAS and SAN systems. With power-loss protection, steady-state 500MB/s performance and over 900 TBW of endurance, it is ideal for SSD caching, small all-flash volumes and application storage.
Reliable Caching for Synology NAS
SSD cache drives in a NAS see constant reads and writes. Consumer SSDs may lack power-loss protection and DSM validation, putting cached data and support at risk.
The SAT5221-480G is validated by Synology, includes power-loss protection and carries over 900 TBW of endurance, making it a dependable cache or app-volume drive for business NAS deployments.
Consistent Steady-State Performance
Synology rates the SAT5221 under steady-state conditions, so its 500MB/s and 90K IOPS figures reflect sustained real-world performance rather than short bursts.
Data Protection Built In
Dedicated capacitors provide power-loss protection, and DSM integration supplies firmware updates and lifespan monitoring.
Setup Instructions
How to Install the Synology SAT5221-480G
- Check that your Synology NAS or SAN model lists the SAT5221 in its compatibility list and update DSM.
- Mount the SSD in a drive tray using the 2.5-inch screw positions (or tool-less clips where supported).
- Insert the tray into a free bay; hot-swap is supported on most Synology models.
- In Storage Manager, create an all-flash storage pool or configure an SSD cache.











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